GeneRanger
GeneRanger is a web-server application that provides access to processed data about the expression of human genes and proteins across human cell types, tissues, and cell lines from several atlases.
Identify targets with:
TargetRanger
GeneRanger
Identify targets with:
TargetRanger
Transcriptomics
ARCHS4, developed by the Ma’ayan Lab, contains over 1 million samples of uniformly processed RNA-seq data from the Gene Expression Omnibus (GEO). The samples were aligned using kallisto with an efficient parallelized cloud workflow. website | citation
GTEx transcriptomics provides bulk RNA-seq data for 54 human tissues collected from postmortem donors. The GTEx database was designed to study the relationship between genetic variation and gene expression across multiple human tissues. website | citation
Human BioMolecular Atlas Program (HubMAP)aims to create a multi-scale spatial atlas of the healthy human body at single-cell resolution by applying advanced technologies and disseminating resources to the community website | citation
Tabula Sapiens is a gene expression atlas created from single cell RNA-seq data collected from multiple tissues of 16 postmortem donors. The processed data contains average expression of each human gene in 486 cell types. website | citation
The Cancer Cell Line Encyclopedia (CCLE) transcriptomics dataset contains gene expression data collected with RNA-seq from over 1000 human pan-cancer cell lines. website | citation
Proteomics
The Human Proteome Map (HPM) contains data from LC-MS/MS proteomics profiling protein expression in 30 human tissues collected from 17 adult postmortem donors. website | citation
The Human Protein Atlas (HPA) contains protein expression data from 44 normal human tissues derived from antibody-based protein profiling using immunohistochemistry. website | citation
The GTEx proteomics dataset has relative protein levels for more than 12,000 proteins across 32 normal human tissues. The data was collected using tandem mass tag (TMT) proteomics to profile tissues collected from 14 postmortem donors. website | citation
The Cancer Cell Line Encyclopedia (CCLE) proteomics dataset contains protein expression in 375 pan-cancer cell lines. Data was collected by quantitative multiplex mass spectrometry proteomics. website | citation
TEK
Short description (from NCBI's Gene Database): This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Gene pages on other sites:
GTEx proteomics: The GTEx proteomics dataset has relative protein levels for more than 12,000 proteins across 32 normal human tissues. The data was collected using tandem mass tag (TMT) proteomics to profile tissues collected from 14 postmortem donors. website | citation